Flexeril Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing
One study found that interactions occurred in 13 percent of patients on oral chemotherapy drugs, with more than 20 percent of those interactions classified as major. Cyclobenzaprine is an oral prescription medication used for muscle spasms from musculoskeletal conditions of sudden onset. It is does flexeril work right away often used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries. Medications are often metabolized by enzymes in the liver so that the medication can be more effectively removed from the body.
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Sometimes, muscle relaxants like cyclobenzaprine are used “off-label” to treat conditions they’re not approved for, such as fibromyalgia. Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute.
What is Flexeril?
This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
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It is unknown if Flexeril passes into breast milk or if it could harm a nursing baby. For most patients, the recommended dose of Flexeril is 5 mg three times a day. Mixing marijuana with the antihistamine hydroxyzine can potentially cause unwanted interactions and shouldn’t be combined. Meet with a counselor and get personalized guidance to the right types and doses of cannabis for your unique needs.
Multiple drug ingestion (including alcohol) is common in deliberate cyclobenzaprine overdose. As management of overdose is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment. Signs and symptoms of toxicity may develop rapidly after cyclobenzaprine overdose; therefore, hospital monitoring is required as soon as possible. The acute oral LD50 of FLEXERIL is approximately 338 and 425 mg/kg in mice and rats, respectively. The plasma concentration of cyclobenzaprine is increased in the elderly (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Elderly). The elderly may also be more at risk for CNS adverse events such as hallucinations and confusion, cardiac events resulting in falls or other sequelae, drug-drug and drug-disease interactions.
- Using both Cyclobenzaprine and weed together can have a wide range of adverse effects.
- While the addictiveness of cyclobenzaprine is being debated, anyone exhibiting problematic patterns of substance use can benefit from addiction treatment.
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- Antidepressants are among the drugs that have caused a number of troubling interactions for chemotherapy patients, especially those with breast cancer.
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Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication. Call your doctor or local poison control center if you think you’ve taken too much of this drug.
Although not all of these side effects may occur, if they do occur they may need medical attention. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Appropriate studies have not been performed on the relationship of age to the effects of cyclobenzaprine extended-release capsules in the pediatric population. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Flexeril only for the indication prescribed.
Addiction Resource does not offer medical diagnosis, treatment, or advice. Only trained and licensed medical professionals can provide such services. If you or anyone you know is undergoing a severe health crisis, call a doctor or 911 immediately. Follow all directions on your prescription label and read all medication guides or instruction sheets. Ask your healthcare professional how you should dispose of any medicine you do not use. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases.
Comparison studies have not shown one skeletal muscle relaxant to be superior to another. Cyclobenzaprine is the most heavily studied and has been shown to be effective for various musculoskeletal conditions. The sedative properties of tizanidine and cyclobenzaprine may benefit patients with insomnia caused by severe muscle spasms.